[GRRN] Cancer clusters around MSW incinerator

From: Stephanie C. Davis (ScD18@WasteReductionRemedies.com)
Date: Tue Sep 05 2000 - 19:24:51 EDT

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    Viel, J., Arveux, P., Baverel, J., Cahn, J. 2000. Soft-tissue sarcoma
    and non-Hodgkin's lymphoma clusters around a municipal solid
    waste incinerator with high dioxin emission levels. Am J Epidemiol
    152(1):13-9

    Overall evidence from epidemiologic studies in the workplace
    suggests that dioxin is a human carcinogen, but whether low doses
    affect the general population remains to be determined. The
    authors examined the spatial distribution of soft-tissue sarcomas
    and non-Hodgkin's lymphomas around a French municipal solid
    waste incinerator with high emission levels of dioxin (16.3 ng
    international toxic equivalency factor/m3). Not consistently
    associated with dioxin exposure,-Hodgkin's disease served as the
    control cancer category. Clusters were identified from 1980 to
    1995 in the area ("departement') of Doubs by applying a spatial
    scan statistic to 26 electoral wards. The most likely and highly
    significant clusters found were identical for soft-tissue sarcomas
    and non-Hodgkin's lymphomas and included the area around the
    municipal solid waste incinerator; standardized incidence ratios
    were 1.44 (observed number of cases = 45, focused test p value =
    0.004) and 1.27 (observed number of cases = 286, focused test p
    value = 0.00003), respectively. Conversely, Hodgkin's disease
    exhibited no specific spatial distribution. Confounding by
    socioeconomic status, urbanization, or patterns of medical referral
    seemed unlikely to explain the clusters. Although consistent, these
    findings should be confirmed by further investigation (e.g., a case-
    control study in which dioxins are measured in biologic tissues)
    before clusters of soft-tissue sarcoma and non-Hodgkin's
    lymphoma are ascribed to dioxin released by the municipal solid
    waste incinerator.

    -- 
           Stephanie  C. Davis - BFA, MPA
       Experienced Professional of Healthcare &
      Non-Residential Waste Programs
    

    Waste Reduction Remedies sm A Multi-Waste Stream, Multi-Material Waste Management Company

    1497 Hopkins Street #2D Berkeley CA 94702-1201 Telephone & Fax: 510/527-8864 Pacific Time E-mail: ScD18@WasteReductionRemedies.com



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